产品货号：
Z26145
中文名称：
SIN1/MAPKAP1抗体
英文名称：
Anti-SIN1/MAPKAP1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SIN1/MAPKAP1 Antibody |
| 指标别名 | JC310;MAPKAP1;MIP1;mSIN1;SAPK interacting protein 1;SIN1;SIN1b;SIN1g;TORC2 subunit MAPKAP1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | MAPKAP1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | MAPKAP1 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human MAPKAP1.The immunogen is located within amino acids 90 - 140 of MAPKAP1. |
| 计算分子量 | 59kDa |
| 成分 | MAPKAP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | MAPKAP1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | MAPKAP1 was initially identified as the human homolog of S.pombe SIN1.Recent evidence has shown that it identical to Mip1,a protein that interacts with MEKK2,a member of the mitogen-activated protein kinase (MAPK) intracellular signaling network.MAPKAP1 is thought to prevent MEKK2 activation and dimerization by forming a complex with the inactive and non-phosphorylated MEKK2,thereby blocking the JNK1/2,ERK1/2,p38 and ERK5 MAPKs.MAPKAP1 has also been shown to play a role in the TOR signaling process,a pathway that is involved in controlling cell growth and proliferation in response to environmental cues such as nutrients,growth factors and hormones.Experiments showed that MAPKAP1 helped to maintain the TOR/rictor assembly but not the TOR/RAPTOR complex,which allowed specific phosphorylation of Akt,a kinase that is believed to couple the growth factor-PI3K signaling pathway to the nutrient-regulated TOR signaling pathway.Multiple alternatively spliced isoforms of MAPKAP1 have been identified. |
| Uniprot ID | Q9BPZ7 |
| 基因名全称 | Mitogen-activated protein kinase associated protein 1 |
| 蛋白名全称 | Mitogen-activated protein kinase associated protein 1 |
| 推荐稀释比 | MAPKAP1 antibody can be used for detection of MAPKAP1 by Western blot at 0.5 ～ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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